沧州康壮化工有限公司经营部  

它是无色或浅黄色透明液体 colorless or slightly yellow clear liquid

相对密度为1.06 relative density: 1.06

常压下b.p.246℃   m.p—20℃ normal pressure b.p.:246℃   m.p:—20℃

闪点121℃ flash point: 121℃

分子式：C₆H₁₂N₂O molecular formula: C₆H₁₂N₂O

分子量128.18 molecular weight: 128.18

二、DMPU的化学性质 Chemical character of DMPU

其结构中由于羰基具有强烈的吸电子效应，因而它是一种非质子的极性溶剂，具有高沸点、高闪点、低熔点，在过滤、蒸馏、溶剂萃取等工艺操作中使用方便；毒性极低，对人体危害微不足道，也减少了对环境的污染；由于它具有极强的溶解性，能溶解有机物、无机物、树脂、聚合物等，并对各种试剂具有活化性质，还能与其它高沸点溶剂混溶；具有极好的稳定性，在热的强碱和酸性条件下都很稳定，还具有耐水性及对光、氧的稳定性。因此DMPU应用到有机化学反应中能促进反应物溶解，加快反应速度，提高反应收率，还能替代毒性较大的溶剂。

Because the carbonyl in its structure is with strongly absorb-electron effect, so it is a kind of non-proton polarity solvent with high boiling point, high flash point and low melting point, use conveniently for many processing operation such as filtration, distillation, solvent extraction, and so on; it is with very low toxicity, so the harm to human body is inappreciable, and reduce the environment pollution; due to its very strong dissolvability, it can dissolve organic matter, inorganic matter, resin, polymer, etc., and activate all kinds of reagent, mix to dissolve the other high boiling point solvents; it is with very good stability, it is stable under the hot strong alkali and acidity condition, it is with water-resistance and light, oxygen stability. Therefore DMPU used for organic chemistry reaction can promote the dissolution of reactants, quicken the reaction speed, increase the efficiency of reaction, and substitute the bigger toxicity solvents.

DMPU在药物制剂中的应用：生物体的表皮是一道生理屏障，它阻止体外物质的进入，因此外用制剂中需要加入能促进皮肤吸收的溶剂。这种溶剂应符合以下需求：活性药物基团能快速可靠地到达损伤的部位：不刺激皮肤，无毒；长时间保存稳定。DMPU能够溶解多种药物，对人体几乎没有毒性，具备以上要求，因此它能作为药物辅料使用。以DMPU和其它辅料及药物配成药剂能促进药物的溶解与混合，增强该药的稳定性和透皮吸收能力，延长药物的作用时间。

DMPU used for producing the medicament preparation: the cuticle of organism is a physiological barrier, which prevent out-body matter from entering, so the preparation for external use need to add the solvent that can promote the skin absorption. The solvent should be accorded with the requirement as below: active medicament can reach the harmed place quickly and credibly; no skin irritation, no toxicity; keep the stability for long term. DMPU can resolve many kinds of medicament, it is nearly no toxicity to human body, can meet above requirement, so it is used as medicament dressing. The medicament made by mixing DMPU, other dressings and medicament can promote the dissolution and mixture of medicament, boost up the stability and pass-skin absorption of medicament, and prolong the effect time of medicament.

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